Letter: tenofovir may be superior to entecavir for treatment‐naïve chronic hepatitis B patients—authors’ reply
نویسندگان
چکیده
LINKED CONTENT This article is linked to Pol et al and Wang papers. To view these articles, visit https://doi.org/10.1111/apt.16197 https://doi.org/10.1111/apt.16323
منابع مشابه
Letter: First-line monotherapies for chronic hepatitis B - indirect comparison between entecavir and tenofovir.
SIRS, In the debate on the use of nucleotide/nucleoside analogues in chronic hepatitis B (CHB), recent guidelines have pointed out that drug-resistant mutations are more frequent with lamivudine, telbivudine or adefovir. For this reason, only entecavir or tenofovir is recommended as first-line monotherapy. 2 As there are no head-to-head comparisons between entecavir and tenofovir, we performed ...
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Background:Tenofovir is among the first-line treatments for chronic hepatitis B (CHB) virus infection. We evaluated the efficacy of Tenofovir in the treatment of Iranian adult patients with CHB. Methods: In a retrospective study, we evaluated 154 HBsAg positive patients referred to Sadoughi hospital in Yazd-Iran for treatment ...
متن کاملComparable efficacy with entecavir monotherapy and tenofovir–entecavir combination in chronic hepatitis B patients
OBJECTIVES The long-term goal for chronic hepatitis B patients is to maintain viral suppression in order to reduce disease progression risk. Because patients with previous treatment failure may have multiple viral resistance mutations, finding effective therapy is challenging. Because recent studies have shown that the combination of entecavir and tenofovir is effective in achieving virological...
متن کاملTenofovir-based alternate therapies for chronic hepatitis B patients with partial virological response to entecavir.
Entecavir (ETV) is a first-line antiviral therapy for treating chronic hepatitis B (CHB); however, some patients have suboptimal response to ETV. Currently, there are limited data on how to approach these patients. Therefore, our aim was to compare the effectiveness of two alternate therapies--tenofovir (TDF) monotherapy and combination therapy of ETV+TDF--in CHB patients with ETV partial virol...
متن کاملEfficacy of tenofovir-based rescue therapy for chronic hepatitis B patients with resistance to lamivudine and entecavir
BACKGROUND/AIMS Tenofovir disoproxil fumarate (TDF) monotherapy for 48 weeks provided a virological response comparable to that of TDF and entecavir (ETV) combination therapy in patients infected with ETV-resistant hepatitis B virus (HBV). Little long-term data in routine clinical practice are available regarding the optimal treatment of patients with ETV-resistant HBV. METHODS We investigate...
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ژورنال
عنوان ژورنال: Alimentary Pharmacology & Therapeutics
سال: 2021
ISSN: ['1365-2036', '0269-2813']
DOI: https://doi.org/10.1111/apt.16340